Method Development and Validation for Simultaneous Estimation of Benidipine Hydrochloride and Metoprolol Succinate in Tablet
نویسندگان
چکیده
منابع مشابه
Simultaneous Estimation of Metoprolol Succinate and Olmesartan
A simple, precise, specific and accurate reverse phase HPLC method has been developed for the simultaneous determination of Metoprolol succinate (METO) and Olmesartan medoxomil (OLME) in tablet dosage form. The chromatographic separation was achieved on inertsil ODS 3V (250 mm×4.6 mm, 5 μm) column using PDA detector. The mobile phase consisting of Buffer (2 ml O-phosphoric acid in 2000 ml milli...
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A binary mixture of Risperidone (RIS) and Trihexyphenidyl hydrochloride (THP) was determined using reversed-phase liquid chromatography method using methanol: acetonitrile: 0.05 M phosphate buffer (pH 3.7) (60:30:10, v/v/v) pumped at a flow rate of 1.0 ml/min. Quantification was achieved with ultraviolet detection at 230 nm over concentration ranges of 0.5-5.0 and 1.0-10.0 μg/ml; mean accuracie...
متن کاملAbsorption Correction Method for Simultaneous Estimation of Metoprolol Succinate and Olmesartan Medoxomil in Combined Tablet Dosage Form
A new, simple, precise, accurate and sensitive UV ‐ Spectrophotometric absorption correction method has been developed for simultaneous determination of Metoprolol Succinate and Olmesartan Medoxomil in combined tablet dosage form. Methanol was used as solvent. Absorbance correction method was based on the property of additivity of absorbances. The two wavelengths on Olmesartan medoxomil curve w...
متن کاملAbsorbance correction method for estimation of telmisartan and metoprolol succinate in combined tablet dosage forms
AIM AND BACKGROUND The present manuscript describes simple, sensitive, rapid, accurate, precise and economical spectrophotometric method for the simultaneous determination of telmisartan and metoprolol succinate in combined tablet dosage form. MATERIALS AND METHODS The method is based on the absorbance correction equations for analysis of both the drugs using methanol as solvent. Telmisartan ...
متن کاملDevelopment of Reverse-Phase HPLC Method for Simultaneous Analysis of Metoprolol Succinate and Hydrochlorothiazide in a Tablet Formulation
Purpose: To develop a simple, sensitive and rapid reverse phase HPLC method for the simultaneous analysis of metoprolol succinate and hydrochlorothiazide in a solid dosage form. Methods: The drugs were analysed by a reverse phase C-18 column using 50mM di-sodium hydrogen phosphate:methanol:acetonitrile in a ratio of 525:225:250 as mobile phase. The flow rate was 1 ml/min and the compounds were ...
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ژورنال
عنوان ژورنال: Journal of Drug Delivery and Therapeutics
سال: 2019
ISSN: 2250-1177
DOI: 10.22270/jddt.v9i6-s.3692